Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/189319142?client_source=feed&format=rss
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Monday, January 23, 2012
Saturday, January 21, 2012
Would You Rather Date Steven Tyler or Ryan Seacrest?
This week, our favorite American Idol judges returned with the season 11 premiere. And while many of the male contestants were smitten upon meeting Jennifer Lopez, the female attention seemed evenly split between Ryan Seacrest and Steven Tyler. (Sorry, Randy!)
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App Giveaway: SOULCALIBUR for iPhone and ipad
The popular arcade fight game, SOULCALIBUR, has just hit the App Store! It is a universal app for iPhone and iPad and includes all 19 characters with all the original
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Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/Swdaydduldo/story01.htm
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Friday, January 20, 2012
Renowned Jamaica producer Winston Riley dies at 65 (AP)
KINGSTON, Jamaica ? Winston Riley, an innovative reggae musician and producer, has died of complications from a gunshot wound to the head. He was 65.
Riley died Thursday at University Hospital of the West Indies, where he had been a patient since November, when he was shot at his house in an upscale neighborhood in the capital of Kingston, his son Kurt Riley said Friday.
Riley also had been shot in August and was stabbed in September last year. His record store in Kingston's downtown business district also was burned down several years ago. Police have said they know of no motives and have not arrested anyone.
Kurt Riley told the Jamaica Observer newspaper that the family did not know what motivated the attacks.
"Unfortunately, Daddy didn't wake up so we could talk to him to find out if there was something he was not telling us," he was quoted as saying. "He was a straightforward man who was allergic to hypocrisy."
As a teenager, Riley founded an influential harmony group, The Techniques, which recorded for pioneer producer Arthur "Duke" Reid. Riley also toured with Byron Lee and later gained fame for producing songs such as "Double Barrel" by Dave Barker and Ansell Collins.
He worked with musicians including Gregory Isaacs, Johnny Osbourne, Sister Nancy and Buju Banton.
Musicologist Kingsley Goodison, who knew Riley for more than 40 years, said he was one of the people responsible for introducing reggae to England.
"Winston Riley is an unsung hero," he said. "He was one of the hardest workers in the business."
Riley also is credited with creating the stalag rhythm, which later influenced hip-hop and dancehall. Unlike his contemporaries who shunned dancehall music, Riley embraced contemporary reggae and had several big hits during the 1980s.
One of his biggest productions was singer Tenor Saw's "Ring The Alarm", which has been sampled by several hip-hop artists.
Riley is survived by several children and grandchildren.
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Exclusive: Pakistan-U.S. ties still on hold over NATO attack (Reuters)
ISLAMABAD (Reuters) ? Ties between the United States and Pakistan are still on hold over a NATO cross-border air attack and Washington should not push Islamabad to go after militant groups including the Haqqani network or bring them to any Afghan peace process, Pakistan's foreign minister told Reuters on Thursday.
"Now that the re-evaluation process is underway as we speak, so till the time that that re-evaluation process in not complete, we cannot start the re-engagement," Hina Rabbani Khar said in an interview.
The November 26 NATO attack, which killed 24 Pakistani soldiers, plunged relations between Washington and Islamabad to their lowest levels in years.
The United States sees Pakistan as critical to its efforts to wind down the war in neighboring Afghanistan, where U.S.-led NATO forces are battling a stubborn Taliban insurgency.
But the NATO incident exacerbated a crisis in relations which erupted after U.S. special forces killed Osama bin Laden in a unilateral raid on Pakistani soil in May last year which embarrassed Pakistan's powerful military.
"I would say they (ties) are conveniently on hold until we start re-engaging," said Khar.
The United States has long sought Pakistani cooperation in tackling the Haqqani network, the Afghan insurgent group now seen as the gravest threat to NATO and Afghan troops.
Pakistan argues that the United States needs to be patient and gain a greater understanding of the region's complexities before acting, and that pressure would only hurt efforts to pacify Afghanistan.
"'Push' is never wise. I think that every country must be allowed to develop their own strategy and their own timing," said a confident Khar, wearing a traditional head scarf and a colorful shawl.
(Reporting by Michael Georgy and Chris Allbritton; Editing by Ed Lane)
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Thursday, January 19, 2012
Focus on glaucoma origins continues path toward potential cure
![[ Back to EurekAlert! ]](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_s4OLK0mG9B61u3HNQyWWI9a246Nq4uGOmHM8eXFp9YSPeOQenN4DSlrcQaIH-EWx6QaLWAFlG1pckT5YnZ_ts9WabG43wD7Pg0r83A1P8=s0-d){kind=small}
Public release date: 17-Jan-2012[ | E-mail |
Share ] Contact: Jason Maderer
maderer@gatech.edu
404-385-2966
Georgia Institute of Technology
Georgia Tech findings advance glaucoma research
Glaucoma is the second leading cause of blindness. Nearly 4 million Americans have the disorder, which affects 70 million worldwide. There is no cure and no early symptoms. Once vision is lost, it's permanent.
New findings at Georgia Tech, published in January during Glaucoma Awareness Month, explore one of the many molecular origins of glaucoma and advance research dedicated to fighting the disease.
Glaucoma is typically triggered when fluid is unable to circulate freely through the eye's trabecular meshwork (TM) tissue. Intraocular pressure rises and damages the retina and optic nerve, which causes vision loss. In certain cases of glaucoma, this blockage results from a build-up of the protein myocilin. Georgia Tech Chemistry and Biochemistry Assistant Professor Raquel Lieberman focused on examining the structural properties of these myocilin deposits.
"We were surprised to discover that both genetically defected as well as normal, or wild-type (WT), myocilin are readily triggered to produce very stable fibrous residue containing a pathogenic material called amyloid," said Lieberman, whose work was published in the most recent Journal of Molecular Biology.
Amyloid formation, in which a protein is converted from its normal form into fibers, is recognized as a major contributor to numerous non-ocular disorders, including Alzheimer's, certain forms of diabetes and Mad Cow disease (in cattle). Scientists are currently studying ways to destroy amyloid fibrils as an option for treating these diseases. Further research, based on Lieberman's findings, could potentially result in drugs that prevent or stop myocilin amyloid formation or destroy existing fibrils in glaucoma patients.
Until this point, amyloids linked to glaucoma had been restricted to the retinal area. In those cases, amyloids kill retina cells, leading to vision loss, but don't affect intraocular pressure.
"The amyloid-containing myocilin deposits we discovered kill cells that maintain the integrity of TM tissue," said Lieberman. "In addition to debris from dead cells, the fibrils themselves may also form an obstruction in the TM tissue. Together, these mechanisms may hasten the increase of intraocular pressure that impairs vision."
Together with her research team, Lieberman produced WT and genetically defected myocilin variants that had been documented in patients who develop glaucoma in childhood or early adulthood. The experiments were conducted in collaboration with Georgia Tech Biology Professor Ingeborg Schmidt-Krey and Stanford Genetics Professor Douglas Vollrath. Three Georgia Tech students also participated in the research: Susan Orwig (Ph.D. graduate, Chemistry and Biochemistry), Chris Perry (current undergraduate, Biochemistry) and Laura Kim (master's graduate, Biology).
###
The National Institutes of Health (award number R01EY021205 from the National Eye Institute) funded the research. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Eye Institute or the National Institutes of Health.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 17-Jan-2012[ | E-mail |
Share ] Contact: Jason Maderer
maderer@gatech.edu
404-385-2966
Georgia Institute of Technology
Georgia Tech findings advance glaucoma research
Glaucoma is the second leading cause of blindness. Nearly 4 million Americans have the disorder, which affects 70 million worldwide. There is no cure and no early symptoms. Once vision is lost, it's permanent.
New findings at Georgia Tech, published in January during Glaucoma Awareness Month, explore one of the many molecular origins of glaucoma and advance research dedicated to fighting the disease.
Glaucoma is typically triggered when fluid is unable to circulate freely through the eye's trabecular meshwork (TM) tissue. Intraocular pressure rises and damages the retina and optic nerve, which causes vision loss. In certain cases of glaucoma, this blockage results from a build-up of the protein myocilin. Georgia Tech Chemistry and Biochemistry Assistant Professor Raquel Lieberman focused on examining the structural properties of these myocilin deposits.
"We were surprised to discover that both genetically defected as well as normal, or wild-type (WT), myocilin are readily triggered to produce very stable fibrous residue containing a pathogenic material called amyloid," said Lieberman, whose work was published in the most recent Journal of Molecular Biology.
Amyloid formation, in which a protein is converted from its normal form into fibers, is recognized as a major contributor to numerous non-ocular disorders, including Alzheimer's, certain forms of diabetes and Mad Cow disease (in cattle). Scientists are currently studying ways to destroy amyloid fibrils as an option for treating these diseases. Further research, based on Lieberman's findings, could potentially result in drugs that prevent or stop myocilin amyloid formation or destroy existing fibrils in glaucoma patients.
Until this point, amyloids linked to glaucoma had been restricted to the retinal area. In those cases, amyloids kill retina cells, leading to vision loss, but don't affect intraocular pressure.
"The amyloid-containing myocilin deposits we discovered kill cells that maintain the integrity of TM tissue," said Lieberman. "In addition to debris from dead cells, the fibrils themselves may also form an obstruction in the TM tissue. Together, these mechanisms may hasten the increase of intraocular pressure that impairs vision."
Together with her research team, Lieberman produced WT and genetically defected myocilin variants that had been documented in patients who develop glaucoma in childhood or early adulthood. The experiments were conducted in collaboration with Georgia Tech Biology Professor Ingeborg Schmidt-Krey and Stanford Genetics Professor Douglas Vollrath. Three Georgia Tech students also participated in the research: Susan Orwig (Ph.D. graduate, Chemistry and Biochemistry), Chris Perry (current undergraduate, Biochemistry) and Laura Kim (master's graduate, Biology).
###
The National Institutes of Health (award number R01EY021205 from the National Eye Institute) funded the research. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Eye Institute or the National Institutes of Health.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2012-01/giot-fog011712.php
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